Cation-Promoted Strain-Release-Driven Access to Functionalized Azetidines from Azabicyclo[1.1.0]butanes. Jaiswal, V.; Mondal, S.; Singh, B.; Singh, V.P.; Saha, J. Angew. Chem. Int. Ed. 2023 (just accepted)(Link)
Fe-Catalyzed Hydroallylation of Unactivated Alkenes with Vinyl Cyclopropanes . Mondal, B.; Hazra, S.; Chatterjee, A.; Patel, M; Saha, J. Org. Lett. 2023, ASAP article (Link)
Experimental and Theoretical Investigation of an Aza-Oxyallyl Cation Templated Intramolecular Arylamination Leading to Oxindole Derivatives Bera, T.; Singh, B.; Gandon, V.; Saha, J. Chem. Eur. J.2022, 28, e202201208 (Link)
Access to 3,3'-disubstituted peroxyoxindole derivatives and α-peroxyamides via azaoxyallyl cation-guided addition of hydroperoxides. Bera, T.; Singh, B.; Jana, M.; Saha, J. Chem. Commun. 2022, 58, 7538. [Link]
Access to densely functionalized spirocyclopentenonyl oxindole frameworks via aza- and carbo-Piancatelli rearrangement. Pramanik, S.; Jagadeesh, C.; Chatterjee, A.; Debnath, S. C.; Saha, J. Org. Biomol. Chem., 2022,20, 5249-5253 [Link]
An Acid Promoted Pseudocine Substitution Manifold of γ-Aminocyclopentenone Enables Divergent Access to Polycyclic Indole Derivatives. Mondal, B.; Jagadeesh, C.; Das, D.; Saha, J. Chem. Commun. 2022, 58, 2504. [Link]
Leveraging the Domino Skeletal Expansion of Thia-/Selenazolidinones via Nitrogen-Atom Transfer in HFIP: Room Temperature Access to Six-Membered S/Se-N Heterocycles. Jaiswal, V.; Godara, M.; Das, D.; Gandon, V.; Saha, J. J. Org. Chem. 2022, 87, 613. [This work is highlighted in Synfacts: DOI: 10.1055/s-0042-1752924]
Unprecedented Reactivity of γ-Amino Cyclopentenone Enables Diversity-Oriented Access to Functionalized Indoles and Indole-Annulated Ring Structures. Jagadeesh, C.; Mondal, B; Pramanik, S.; Das, D Saha, J. Angew. Chem. Int. Ed. 2021. 60, 8808 (DOI: 10.1002/anie.202016015)
An Approach to α- and β-Amino Peroxides via Lewis Acid Catalyzed Ring Opening-Peroxidation of Donor-Acceptor Aziridines and N-Activated Aziridines. Singh, K.; Kumar, P.; Jagadeesh, C.; Patel, M.; Das, D.; Saha, J. Adv. Synth. Catal. 2020. 363, 4130 (DOI: 10.1002/adsc.202000815).
Recent Developments on the Synthesis of Various Sulfur‐Containing Heterocycles via [3+2]‐ and [4+2]‐Cycloaddition Reactions with Thiocarbonyls. Jaiswal, V.; Mondal, B.; Saha, J. Asian. J. Org. Chem. 2020.9, 1466 (DOI: org/10.1002/ajoc.202000238)
Multicomponent, Tandem 1,3-and 1,4-Bisarylation of Donor-Acceptor Cyclopropanes and Cyclobutanes with Electron-Rich Arenes and Hypervalent Arylbismuth Reagets. Mondal, B.; Das, D.; Saha, J. Org. Lett. 2020. 22, 5115. (DOI: org/10.1021/acs.oerlett.0c01702).
One-Step Assembly of Functionalized Morpholinones and 1,4-Oxazepane-3-ones via [3+3]- and [3+4]-Annulation of Aza-oxyallyl Cation and Amphoteric Compounds. Bera, T.; Singh, B.; Hamlin, T. A.; Sahoo, S.C.; Saha, J. J. Org. Chem. 2019. 84, 15255 (DOI: org/10.1021/acs.joc.9b02269).
[3+2]-Annulation of Azaoxyallyl Cations and Thiocarbonyls for the Assembly of Thiazolidin-4-ones. Jaiswal, V.; Mondal, B.; Singh, K.; Das, D.; Saha, J. Org. Lett. 2019. 21, 5848 (DOI: 10.1021/acs.orglett.9b01933)
Lewis Acid Catalyzed Annulation of Spirocyclic Donor-Acceptor Cyclopropanes with exo-Heterocyclic Olefins: Access to Highly Functionalized bis-spirocyclopentane Oxindole Frameworks. Singh, K.; Pramanik, S.; Hamlin, T. A.; Mondal, B.; Das, D.; Saha, J. Chem. Commun. 2019, 55, 7069 (DOI: 10.1039/C9CC03393A).
Lewis Acid Catalyzed Nucleophilic Ring-Opening and 1,3-Bisfunctionalization of Donor-Acceptor Cyclopropanes with Hydroperoxides: Access to Highly Functionalized Peroxy/(α-Heteroatom Substituted) Peroxy Compounds. Singh, K.; Bera, T.; Jaiswal, V.; Biswas, S.; Mondal, B.; Das, D.; Saha, J. J. Org. Chem. 2019, 84, 710 (DOI: org/10.1021/acs.joc.8b02561)
Uses of K2S2O8 in Metal Catalyzed and Metal Free Oxidative Transformations. Mandal, S.; Bera, T.; Dubey, G.; Saha, J*; Laha, J.* ACS Catal. 2018, 8, 5085.(DOI: 10.1021/acscatal.8b00743).
Publications from PhD/Post-doc
11. Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs. OConnor, L. J.; Saha. J.; Corner, C.C; Evans, C.N.G.; Stratford, M.R.L.; Hammond, E. M.; Conway, S. J. Nature Protocols. 2016, 11, 784.
10. Efficient Synthesis of 2-Nitroimidazole derivatives and the Bioreductive Clinical Candidate Evofosfamide(TH-302). OConnor, L. J.; Corner, C.C.; Saha. J.; Evans, C.N.G.; Stratford, M.R.L.; Hammond, E. M.; Conway, S. J. Org.Chem.Front. 2015. 2, 1026.
9. An uncharged oxetanylsulfoxide as a covalent modifier for improving aqueous solubility. Skoda, E, Sachar, J.; Saha. J.; Wipf, P. ACS. Med. Chem. Lett. 2014, 5, 900.
7. Copper Catalyst-Controlled Site Selective Allenylation of Ketones and Aldehydes with Propargyl Boronates. Fandrick, K.R.; Ogikubo, J.; Fandrick, D.R.; Patel, N.D.; Saha, J.; Lee, H.; Ma, S.; Grinberg, N.; Busacca, C.A.; Senanayake, C.H. Org. Lett. 2013, 15, 1214.
6. Glycosylations With a Septanosyl Fluoride Donor Lacking a C2 Protecting Group. Saha, J.; Peczuh. M. W. Tetrahedron Lett. 2012, 53, 5667.
5. Discovery of a Phosphine-Mediated Cycloisomerization of AlkynelHemiketals: Access to Spiroketals and Dihydropyrazoles Via Tandem Reactions. Saha, J.; Lorenc, C.; Surana,B.; Peczuh, M.W. J. Org. Chem. 2012, 77, 3846.
4. Synthesis and Properties of Septanose Carbohydrates. Saha, J.; Peczuh, M. W. Advances in Carbohydrate Chemistry and Biochemistry. 2011, 66, 121.
3. Zinc Catalyzed Allenylations of Aldehydes and Ketones. Fandrick, D. R*.;Saha, J.; Fandrick, K. R.; Sanyal, S.; Lee, H.; Roschanger, F.; Song, J. J.; Senanayake, C. H. Org. Lett, 2011,13, 5616.
2. Expanding the Scopes of Aminosugars: Synthesis of 2-Amino SeptanosylGlycoconjugates Using Septanosyl Fluoride Donor. Saha, J.; Peczuh, M. W. Chem. Eur. J. 2011,17, 7357.
1. Access to Ring-Expanded Analogues of 2-Amino Sugars. Saha, J.; Peczuh, M. W. Org. Lett. 2009, 11, 4482.